Cornell Researchers Confirm Marfan Syndrome in Domestic Cats

Cornell University scientists have identified the first genetically confirmed cases of Marfan syndrome in domestic felines, based on two unusually long‑legged brothers. Genetic analysis revealed that both cats carried two altered copies of a gene known to cause the rare connective‑tissue disorder in humans, which can affect the eyes, heart, and blood vessels. Despite the mutation, the cats survived into adulthood, suggesting that the genetic change still permits some normal function. This discovery provides a new animal model for studying Marfan syndrome and may help veterinarians recognize and manage similar conditions in cats.