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Nobel-Winning Scientist Explains How He Developed Optogenetics

WHY IT MATTERS

Optogenetics has the potential to revolutionize the treatment of neuropsychiatric conditions and restore sight in people with visual impairment, offering new hope for those affected by these conditions.

What happened

Karl Deisseroth, a neuroscientist at Stanford University, has explained how he made his Nobel-winning discovery of optogenetics, a technique that allows researchers to control the activity of neurons with light. Deisseroth's work involved inserting a gene from a single-celled algae into rat cells, which responded to light by activating. This breakthrough led to the development of optogenetics, which has been used to control living mice and is now being explored for its potential to restore sight in people with visual impairment.

PRIMARY SOURCES

Using light to control brain cells – neuroscientist Karl Deisseroth explains how he made his Nobel-winning discovery

The Conversation US · Karl Deisseroth, D. H. Chen Professor, Professor of Bioengineering and of Psychiatry and Behavioral Sciences, Stanford University · CC BY-ND; link/attribution intake only—no edited republication

CORRECTIONS & UPDATES

  1. Revision 1 · Initial ingestion · Oct 15, 2026, 1:31 PM
  2. Revision 2 · Source update detected · Oct 15, 2026, 1:31 PM
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