Global Polio Eradication Initiative Strengthens Use of Inactivated Polio Vaccines

The Global Polio Eradication Initiative (GPEI) has recommended that countries transition to a three-dose inactivated polio vaccine (IPV) schedule in routine immunization. This change aims to increase immunity levels, particularly in high-risk settings. The third dose of IPV should be delivered preferably through hexavalent vaccine introduction, which combines IPV with other routine vaccines. In outbreak response, a second fractional or full dose of IPV can be considered to boost mucosal immunity if an outbreak lasts beyond six months after the first dose.